Under Guidance 213, which administration routes are regulated for medically important antimicrobials?

Under Guidance 213, which administration routes are regulated for medically important antimicrobials?

• A. Feed and water administration of medically important antimicrobials
• B. Topical application only
• C. Injection only in animals over 1 year old
• D. Human medicine routes only

Answer: (A)

Guidance 213 concentrates on how medically important antimicrobials are used in food-producing animals, with emphasis on routes that affect groups of animals in production settings. The administration route that is regulated under this guidance is delivery through feed or drinking water. These routes are targeted because they enable mass administration to many animals and have a higher potential to drive antimicrobial resistance, so they require veterinary oversight and, often, a veterinary directive or prescription to ensure use is for disease treatment, prevention, or control rather than other purposes. Other routes like topical application or injections aren’t the focus of Guidance 213, and human medicine routes fall outside its scope since the guidance is about veterinary use in animals.

Guidance 213 concentrates on how medically important antimicrobials are used in food-producing animals, with emphasis on routes that affect groups of animals in production settings. The administration route that is regulated under this guidance is delivery through feed or drinking water. These routes are targeted because they enable mass administration to many animals and have a higher potential to drive antimicrobial resistance, so they require veterinary oversight and, often, a veterinary directive or prescription to ensure use is for disease treatment, prevention, or control rather than other purposes.

Other routes like topical application or injections aren’t the focus of Guidance 213, and human medicine routes fall outside its scope since the guidance is about veterinary use in animals.